3d Molecular Designs Dna Replication Activity Guide
Flow of Genetic Information Kit©
Don't be surprised if one of your students blurts "Now I get it!" while using our Flow of Genetic Information Kit©. Manipulating the kit's color-coded foam nucleotides and placemats, students:
- Model replication of the leading and lagging strands of DNA.
- Model transcription as they copy one strand of DNA into mRNA using an RNA polymerase.
- Model translation/protein synthesis as they decode the mRNA into protein on the ribosome placemat.
Your students can then explore the folding of the protein into its final 3D shape using the popular Amino Acid Starter Kit©.
Photo Gallery
Replication: DNA Polymerase Catalyzes the Synthesis of New DNA
Leading Strand (Top) & Lagging Strand (Bottom)
Semiconservative Replication
Transcription: RNA Polymerase Binds to DNA
Transcription: The mRNA is Synthesized
Transcription: The mRNA Transcript is Released
Translation: Ribosomal Subunits Bind to the mRNA
Translation: Amino Acids are Added to the Growing Protein
Translation: Amino Acids are Added to the Growing Protein
Translation: The mRNA Transcript is Released
Replacement DNA and RNA Nucleotide Set
Side Chain Expansion Pack
tRNA Expansion Pack
Kit Contents
Flow of Genetic Information Kit© |
Placemats |
1 DNA Replication Placemat (12'' x 19'') |
1 Transcription Placemat (12'' x 19'') |
1 Translation Placemat (12'' x 19'') |
2 DNA Polymerase Ovals |
1 Transcription Bridge |
Sticky-Back Foam |
3 Pieces of Orange Sticky-Back Foam for Replication Placemat |
5 Pieces of Red Sticky-Back Foam for Transcription Placemat |
3 Pieces of Purple Sticky-Back Foam for Translation Placemat |
4 Pieces of Gray Sticky-Back Foam for Polymerase Ovals |
1 Sheet of Stickers |
MAPS |
2 DNA Sequence Maps (I and II) |
2 RNA Sequence Maps (I and II) |
9 Tan tRNA Molecules |
1 Tan Release Factor |
10 White Amino Acids |
DNA Nucleotides |
40 Red Adenine 24 Gray Adenine |
40 Yellow Thymine 24 Gray Thymine |
40 Blue Cytosine 24 Gray Cytosine |
40 Green Guanine 24 Gray Guanine |
RNA Nucleotides |
10 Red Adenine |
10 White Uracil |
10 Blue Cytosine |
10 Green Guanine |
1 Genetic Codon Mini Chart |
Flow of Genetic Information Kit © Side Chain Expansion Pack |
Amino Acid Side Chains |
1 each Isoleucine, Glutamic Acid, Methionine and Proline |
2 each Cysteine and Histidine |
Clips |
1 each Red and Blue Clips |
2 each Green and White Clips |
4 Yellow Clips |
Flow of Genetic Information Kit © Replacement Nucleotide Set |
DNA Nucleotides |
40 Red Adenine |
40 Yellow Thymine |
40 Blue Cytosine |
40 Green Guanine |
RNA Nucleotides |
10 Red Adenine |
10 White Uracil |
10 Blue Cytosine |
10 Green Guanine |
Flow of Genetic Information Kit © tRNA Expansion Pack |
3 sheets of brown generic tRNAs |
1 sheet of white amino acids |
1 sheet of blank optional stickers |
Flow of Genetic Information Kit© Teacher Resources
Flow of Genetic Information Kit Contents and Assembly
Find information about the contents of your Flow of Genetic Information Kit© and directions for assembling the pieces so you and your students can start exploring DNA replication, RNA transcription and translation/protein synthesis.
Flow of Genetic Information Kit Teacher Notes
This activity guide will help you consider different ways you may use these materials. We encourage you to modify these lessons and activities to meet the learning objectives and needs of your specific students.
Product Details
Grade Level
Middle School
High School
College
Students per Group
4
Warnings
Choking Hazard
Science Education Product
California Proposition 65
List Price
Flow of Genetic Information Kit©
$119 (FGIK-01)
$321 (FGIK-03)
$625 (FGIK-06)
Additional DNA & RNA Nucleotide Set
$23 (FGIK-ANS)
Side Chain Expansion Pack
$29 (FGIK-SCEP)
tRNA Expansion Pack
$14 (FGIK-TEP)
Teacher Tips
Please allot approximately 45 minutes to assemble the first kit and 30 minutes for each additional kit (if you have more than one). Colors may fade. Consider storing foam kits in a dark location such as a closet, cabinet or drawer.
If you wish to use the replication, transcription and translation placements simultaneously in your classroom, you will need to purchase a Replacement DNA & RNA Nucleotide Set to ensure that you have enough pieces.
If you have the Amino Acid Starter Kit © , the appropriate side chains from that kit can be inserted into the 10 white amino acids included with the Flow of Genetic Information Kit © . You can also purchase the Side Chain Expansion Pack described above.
You may wish to use the gray nucleotides to make the new "daughter" strands in the replication activity, in order to call student attention to the newly-synthesized DNA. You can also use them to model the different patterns that emerge in the Meselson and Stahl experiment that determined how the process of DNA replication occurs.
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3d Molecular Designs Dna Replication Activity Guide
Source: https://www.3dmoleculardesigns.com/Education-Products/Flow-of-Genetic-Information-Kit.htm
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